Helena
Ostolaza Etxabe
Helena Ostolaza Etxabe-rekin lankidetzan egindako argitalpenak (37)
2024
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Membrane Interaction Characteristics of the RTX Toxins and the Cholesterol-Dependence of Their Cytolytic/Cytotoxic Activity
International Journal of Molecular Sciences, Vol. 25, Núm. 6
2023
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Kukutxeztula: hurbileko begirada bat
Elhuyar: zientzia eta teknika, Núm. 351, pp. 80-84
2022
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Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model
Small, Vol. 18, Núm. 13
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Four Cholesterol-Recognition Motifs in the Pore-Forming and Translocation Domains of Adenylate Cyclase Toxin Are Essential for Invasion of Eukaryotic Cells and Lysis of Erythrocytes
International Journal of Molecular Sciences, Vol. 23, Núm. 15
2021
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Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size
FEBS Journal, Vol. 288, Núm. 23, pp. 6795-6814
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Kukutxeztula: «gainditutako» gaitz baten itzulera
Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 39, pp. 61-78
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MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants
JACC: Basic to Translational Science, Vol. 6, Núm. 11, pp. 815-827
2020
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Cholesterol efflux efficiency of reconstituted HDL is affected by nanoparticle lipid composition
Biomedicines, Vol. 8, Núm. 10
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Hiperkolesterolemia Familiarra: patofisiologia, diagnostikoa eta tratamendua
Osagaiz: osasun-zientzien aldizkaria, Vol. 4, Núm. 1, pp. 69-80
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Irreversible versus repairable membrane poration: differences in permeabilization elicited by Bordetella Adenylate Cyclase Toxin and its hemolysin domain in macrophages
FEBS Journal, Vol. 287, Núm. 9, pp. 1798-1815
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Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR
Scientific reports, Vol. 10, Núm. 1, pp. 1727
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Pathophysiology of type 2 diabetes mellitus
International Journal of Molecular Sciences, Vol. 21, Núm. 17, pp. 1-34
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Statin treatment-induced development of type 2 diabetes: From clinical evidence to mechanistic insights
International Journal of Molecular Sciences, Vol. 21, Núm. 13, pp. 1-25
2019
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Membrane permeabilization by bordetella adenylate cyclase toxin involves pores of tunable size
Biomolecules, Vol. 9, Núm. 5
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Membrane permeabilization by pore-forming rtx toxins: What kind of lesions do these toxins form?
Toxins, Vol. 11, Núm. 6
2018
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Characterization of the intrinsic phospholipase A1 activity of bordetella pertussis adenylate cyclase toxin
Toxins, Vol. 10, Núm. 12
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Familial hypercholesterolemia: The most frequent cholesterol metabolism disorder caused disease
International Journal of Molecular Sciences, Vol. 19, Núm. 11
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Membrane repair mechanisms against permeabilization by pore-forming toxins
Toxins, Vol. 10, Núm. 6
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Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition
PLoS ONE, Vol. 13, Núm. 10
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Validation of LDLr activity as a tool to improve genetic diagnosis of familial hypercholesterolemia: A retrospective on functional characterization of LDLr variants
International Journal of Molecular Sciences, Vol. 19, Núm. 6