Publications by the researcher in collaboration with Helena Ostolaza Etxabe (37)

2024

  1. Membrane Interaction Characteristics of the RTX Toxins and the Cholesterol-Dependence of Their Cytolytic/Cytotoxic Activity

    International Journal of Molecular Sciences, Vol. 25, Núm. 6

2023

  1. Kukutxeztula: hurbileko begirada bat

    Elhuyar: zientzia eta teknika, Núm. 351, pp. 80-84

2022

  1. Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model

    Small, Vol. 18, Núm. 13

  2. Four Cholesterol-Recognition Motifs in the Pore-Forming and Translocation Domains of Adenylate Cyclase Toxin Are Essential for Invasion of Eukaryotic Cells and Lysis of Erythrocytes

    International Journal of Molecular Sciences, Vol. 23, Núm. 15

2021

  1. Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size

    FEBS Journal, Vol. 288, Núm. 23, pp. 6795-6814

  2. Kukutxeztula: «gainditutako» gaitz baten itzulera

    Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 39, pp. 61-78

  3. MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants

    JACC: Basic to Translational Science, Vol. 6, Núm. 11, pp. 815-827

2020

  1. Cholesterol efflux efficiency of reconstituted HDL is affected by nanoparticle lipid composition

    Biomedicines, Vol. 8, Núm. 10

  2. Hiperkolesterolemia Familiarra: patofisiologia, diagnostikoa eta tratamendua

    Osagaiz: osasun-zientzien aldizkaria, Vol. 4, Núm. 1, pp. 69-80

  3. Irreversible versus repairable membrane poration: differences in permeabilization elicited by Bordetella Adenylate Cyclase Toxin and its hemolysin domain in macrophages

    FEBS Journal, Vol. 287, Núm. 9, pp. 1798-1815

  4. Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR

    Scientific reports, Vol. 10, Núm. 1, pp. 1727

  5. Pathophysiology of type 2 diabetes mellitus

    International Journal of Molecular Sciences, Vol. 21, Núm. 17, pp. 1-34

  6. Statin treatment-induced development of type 2 diabetes: From clinical evidence to mechanistic insights

    International Journal of Molecular Sciences, Vol. 21, Núm. 13, pp. 1-25

2019

  1. Membrane permeabilization by bordetella adenylate cyclase toxin involves pores of tunable size

    Biomolecules, Vol. 9, Núm. 5

  2. Membrane permeabilization by pore-forming rtx toxins: What kind of lesions do these toxins form?

    Toxins, Vol. 11, Núm. 6

2018

  1. Characterization of the intrinsic phospholipase A1 activity of bordetella pertussis adenylate cyclase toxin

    Toxins, Vol. 10, Núm. 12

  2. Familial hypercholesterolemia: The most frequent cholesterol metabolism disorder caused disease

    International Journal of Molecular Sciences, Vol. 19, Núm. 11

  3. Membrane repair mechanisms against permeabilization by pore-forming toxins

    Toxins, Vol. 10, Núm. 6

  4. Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition

    PLoS ONE, Vol. 13, Núm. 10

  5. Validation of LDLr activity as a tool to improve genetic diagnosis of familial hypercholesterolemia: A retrospective on functional characterization of LDLr variants

    International Journal of Molecular Sciences, Vol. 19, Núm. 6