Biophysics and Biochemistry of Macromolecular Interactions Laboratory
Responsable: César Martín Plagaro
Centro (uo): IBF Instituto Biofisika
Correo electrónico: cesar.martin@ehu.eus
Página web: https://www.biofisika.org/en/research/biophysics-and-biochemistry-macromolecular-interactions-laboratory
We are an interdisciplinary research group combining biophysical, cell biology, biochemistry and molecular biology methodologies. Two are our main research focuses are:The study of the molecular mechanisms that underlie protein-protein and protein-membrane interactions, using bacterial toxins as a model system, in particular, the adenylate cyclase toxins, which are essential virulence factors produced by different bacterial pathogens (e.g. Bordetella pertussis, Escherichia coli).Understanding the molecular mechanism that leads to genetic/hereditary hypercholesterolemia and cardiovascular disease. We do translational research by assessing pathogenic variants of LDLR, ApoB-100 and PCSK9 to provide a certain genetic diagnosis of the disease.
Investigadores/as
Clasificaciones
- Centros (c): IBF Instituto Biofisika