Publications by the researcher in collaboration with Diego Marcelo Guérin Aguilar (28)

2021

  1. Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA

    Science Advances, Vol. 7, Núm. 42

2020

  1. Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria

    Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945

  2. Membrane fluidity adjusts the insertion of the transacylase PlsX to regulate phospholipid biosynthesis in Gram-positive bacteria

    Journal of Biological Chemistry, Vol. 295, Núm. 7, pp. 2136-2147

  3. The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM

    Current Research in Structural Biology, Vol. 2, pp. 89-103

2019

  1. Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases

    Methods in Enzymology (Academic Press Inc.), pp. 261-279

  2. Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

    Journal of Molecular Biology, Vol. 431, Núm. 2, pp. 444-461

  3. Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC

    Journal of Biological Chemistry, Vol. 294, Núm. 50, pp. 19066-19080

2018

  1. The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria

    ACS Chemical Biology, Vol. 13, Núm. 1, pp. 131-140

2017

  1. Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

    Structure, Vol. 25, Núm. 7, pp. 1034-1044.e3

  2. Structural Snapshots of α-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases

    Angewandte Chemie - International Edition, Vol. 56, Núm. 47, pp. 14853-14857

  3. Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria

    Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1862, Núm. 11, pp. 1355-1367

  4. The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

    Journal of Biological Chemistry, Vol. 292, Núm. 32, pp. 13097-13110

2016

  1. Structural Basis of Glycogen Biosynthesis Regulation in Bacteria

    Structure, Vol. 24, Núm. 9, pp. 1613-1622

  2. Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

    Nature Communications, Vol. 7

  3. The conformational plasticity of glycosyltransferases

    Current Opinion in Structural Biology, Vol. 40, pp. 23-32

2015

  1. A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

    Angewandte Chemie - International Edition, Vol. 54, Núm. 34, pp. 9898-9902

  2. Secondary structure reshuffling modulates glycosyltransferase function at the membrane

    Nature Chemical Biology, Vol. 11, Núm. 1, pp. 16-18

  3. The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053

    Journal of Biological Chemistry, Vol. 290, Núm. 52, pp. 31077-31089

  4. Triatoma virus recombinant VP4 protein induces membrane permeability through dynamic pores

    Journal of Virology, Vol. 89, Núm. 8, pp. 4645-4654

2014

  1. Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis

    ACS Chemical Biology, Vol. 9, Núm. 7, pp. 1567-1575