Publicaciones en las que colabora con Francisco J. Palacios Gambra (65)
2024
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Antileishmanial Effect of 1,5- and 1,8-Substituted Fused Naphthyridines
Molecules, Vol. 29, Núm. 1
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Aza-Povarov Reaction. A Method for the Synthesis of Fused Tetracyclic Chromeno[4,3-d]pyrido[1,2-a]pyrimidines
Journal of Organic Chemistry, Vol. 89, Núm. 2, pp. 1099-1107
2023
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Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions
Antibiotics, Vol. 12, Núm. 1
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Synthesis of Fused Nitrogenated Heterocycles: Intramolecular Povarov Reaction
Advances in Organic Synthesis (Bentham Science Publishers), pp. 40-111
2022
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Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group
Pharmaceuticals, Vol. 15, Núm. 5
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The design and discovery of topoisomerase I inhibitors as anticancer therapies
Expert Opinion on Drug Discovery, Vol. 17, Núm. 6, pp. 581-601
2021
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A dual-sensor-based screening system for in vitro selection of tdp1 inhibitors
Sensors, Vol. 21, Núm. 14
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A patent review of topoisomerase I inhibitors (2016–present)
Expert Opinion on Therapeutic Patents, Vol. 31, Núm. 6, pp. 473-508
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Design, synthesis and cytotoxic evaluation of diphenyl(quinolin-8-yl)phosphine oxides
Tetrahedron Letters, Vol. 70
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Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents
Bioorganic and Medicinal Chemistry, Vol. 40
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Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1b (top1b)
Pharmaceuticals, Vol. 14, Núm. 8
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Naphthyridine derivatives induce programmed cell death in naegleria fowleri
Pharmaceuticals, Vol. 14, Núm. 10
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Simple and fast dna based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1
Pharmaceutics, Vol. 13, Núm. 8
2020
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Fused 1,5-Naphthyridines: Synthetic Tools and Applications
Molecules (Basel, Switzerland), Vol. 25, Núm. 15
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New Challenges in Drug Discovery – July 8–11, 2019, Vitoria-Gasteiz, Spain
ChemMedChem
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Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents
Dalton Transactions, Vol. 49, Núm. 23, pp. 7852-7861
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Parasitic infectious diseases
European Journal of Medicinal Chemistry
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Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives
European Journal of Medicinal Chemistry, Vol. 195
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Synthetic strategies, reactivity and applications of 1,5-naphthyridines
Molecules, Vol. 25, Núm. 14
2019
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Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents
European Journal of Medicinal Chemistry, Vol. 162, pp. 18-31