Laboratory of Aggregation and Glial Response
Arduraduna: Nora Bengoa Vergniory
Ikastegia: Achucarro Basque Center for Neuroscience
Posta elektronikoa: nora.bv@achucarro.org
Web-orria: https://www.achucarro.org/es/laboratory/aggregation-and-glial-response/
Our research focusses on alpha-synuclein aggregation and neuroinflammation in Parkinson’s disease. Even though it is known that alpha-synuclein aggregation and neuroinflammation are key features of Parkinson’s disease progression there are still many unanswered questions. Where does the toxic aggregation begin? How does it spread? Which cells respond to it? How can we prevent these processes? In order to study glial activation and the aggregation process, and answer these questions we benefit from access to genetic models, patient-derived induced pluripotent stem (iPS) cells, human tissue and alpha-synuclein PLA-based assays. This technology will help us provide novel insights of the role alpha-synuclein oligomers and glial activation play in Parkinson’s and so, could be used to identify new treatments
Ikertzaileak
Sailkapenak
- Ikastegiak: Achucarro Basque Center for Neuroscience