Publicaciones en colaboración con investigadores/as de Hospital Universitario de la Princesa (33)

2020

  1. Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease

    Antioxidants, Vol. 9, Núm. 8, pp. 1-20

  2. Immune Responses and Anti-inflammatory Strategies in a Clinically Relevant Model of Thromboembolic Ischemic Stroke with Reperfusion

    Translational Stroke Research, Vol. 11, Núm. 3, pp. 481-495

  3. Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization

    Pharmacological Research, Vol. 152

2019

  1. Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux

    Journal of Pineal Research, Vol. 67, Núm. 1

2018

  1. The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities

    Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182

  2. Altered excitability and exocytosis in chromaffin cells from the R6/1 mouse model of Huntington's disease is linked to over-expression of mutated huntingtin

    Journal of Neurochemistry, Vol. 147, Núm. 4, pp. 454-476

  3. Dual antidepressant duloxetine blocks Nicotinic receptor currents, calcium signals and exocytosis in chromaffin cells stimulated with acetylcholine

    Journal of Pharmacology and Experimental Therapeutics, Vol. 367, Núm. 1, pp. 28-39

  4. Hydrogen sulphide facilitates exocytosis by regulating the handling of intracellular calcium by chromaffin cells

    Pflugers Archiv European Journal of Physiology, Vol. 470, Núm. 8, pp. 1255-1270

2017

  1. Clinical profile and satisfaction with anticoagulated treatment in patients with non-valvular atrial fibrillation attended in internal medicine and neurology departments of Spain

    Revista de Neurologia, Vol. 65, Núm. 8, pp. 361-367

  2. ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels

    Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359

  3. Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease

    Scientific Reports, Vol. 7

  4. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

    ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81

  5. Inclusion complex of ITH12674 with 2-hydroxypropyl-β-cyclodextrin: Preparation, physical characterization and pharmacological effect

    Carbohydrate Polymers, Vol. 157, pp. 94-104

  6. Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

    Redox Biology, Vol. 12, pp. 1040-1051

  7. NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 46, pp. 12315-12320

  8. Novel multitarget hybrid compounds for the treatment of alzheimer’s disease

    Current Topics in Medicinal Chemistry, Vol. 17, Núm. 9, pp. 1027-1043

  9. Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices

    Neuropharmacology, Vol. 116, pp. 110-121

2016

  1. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice

    Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3030-3045

  2. Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

    Pharmacology and Therapeutics, Vol. 157, pp. 84-104

  3. Regulation by L channels of Ca2+-evoked secretory responses in ouabain-treated chromaffin cells

    Pflugers Archiv European Journal of Physiology, Vol. 468, Núm. 10, pp. 1779-1792