Publicacions (18) Publicacions de Natalia Comino González

2024

  1. In-Hydrogel Cell-Free Protein Expression System as Biocompatible and Implantable Biomaterial

    ACS Applied Materials and Interfaces, Vol. 16, Núm. 13, pp. 15993-16002

  2. Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters

    ACS Applied Materials and Interfaces, Vol. 16, Núm. 1, pp. 833-846

2022

  1. Intraparticle Macromolecular Migration Alters the Structure and Function of Proteins Reversibly Immobilized on Porous Microbeads

    Advanced Materials Interfaces, Vol. 9, Núm. 18

2021

  1. Intraparticle Kinetics Unveil Crowding and Enzyme Distribution Effects on the Performance of Cofactor-Dependent Heterogeneous Biocatalysts

    ACS Catalysis, Vol. 11, Núm. 24, pp. 15051-15067

2020

  1. DESign of Sustainable One-Pot Chemoenzymatic Organic Transformations in Deep Eutectic Solvents for the Synthesis of 1,2-Disubstituted Aromatic Olefins

    Frontiers in Chemistry, Vol. 8

  2. Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria

    Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945

  3. Microcompartmentalized cell-free protein synthesis in hydrogel μ-channels

    ACS Synthetic Biology, Vol. 9, Núm. 11, pp. 2971-2978

  4. The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM

    Current Research in Structural Biology, Vol. 2, pp. 89-103

2019

  1. Structural basis of glycogen metabolism in bacteria

    Biochemical Journal, Vol. 476, Núm. 14, pp. 2059-2092

2017

  1. Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases

    Journal of Biological Chemistry, Vol. 292, Núm. 15, pp. 6255-6268

  2. Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

    Structure, Vol. 25, Núm. 7, pp. 1034-1044.e3

2016

  1. Molecular basis of membrane association by the phosphatidylinositol mannosyltransferase PimA enzyme from mycobacteria

    Journal of Biological Chemistry, Vol. 291, Núm. 27, pp. 13955-13963

  2. Structural Basis of Glycogen Biosynthesis Regulation in Bacteria

    Structure, Vol. 24, Núm. 9, pp. 1613-1622

2015

  1. A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

    Angewandte Chemie - International Edition, Vol. 54, Núm. 34, pp. 9898-9902

  2. Secondary structure reshuffling modulates glycosyltransferase function at the membrane

    Nature Chemical Biology, Vol. 11, Núm. 1, pp. 16-18

  3. The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053

    Journal of Biological Chemistry, Vol. 290, Núm. 52, pp. 31077-31089

2014

  1. Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis

    ACS Chemical Biology, Vol. 9, Núm. 7, pp. 1567-1575

2013

  1. Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria

    Journal of Biological Chemistry, Vol. 288, Núm. 41, pp. 29797-29808