Natalia
Comino González
Publicaciones (18) Publicaciones de Natalia Comino González
2024
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In-Hydrogel Cell-Free Protein Expression System as Biocompatible and Implantable Biomaterial
ACS Applied Materials and Interfaces, Vol. 16, Núm. 13, pp. 15993-16002
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Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters
ACS Applied Materials and Interfaces, Vol. 16, Núm. 1, pp. 833-846
2022
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Intraparticle Macromolecular Migration Alters the Structure and Function of Proteins Reversibly Immobilized on Porous Microbeads
Advanced Materials Interfaces, Vol. 9, Núm. 18
2021
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Intraparticle Kinetics Unveil Crowding and Enzyme Distribution Effects on the Performance of Cofactor-Dependent Heterogeneous Biocatalysts
ACS Catalysis, Vol. 11, Núm. 24, pp. 15051-15067
2020
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DESign of Sustainable One-Pot Chemoenzymatic Organic Transformations in Deep Eutectic Solvents for the Synthesis of 1,2-Disubstituted Aromatic Olefins
Frontiers in Chemistry, Vol. 8
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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Microcompartmentalized cell-free protein synthesis in hydrogel μ-channels
ACS Synthetic Biology, Vol. 9, Núm. 11, pp. 2971-2978
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The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM
Current Research in Structural Biology, Vol. 2, pp. 89-103
2019
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Structural basis of glycogen metabolism in bacteria
Biochemical Journal, Vol. 476, Núm. 14, pp. 2059-2092
2017
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Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases
Journal of Biological Chemistry, Vol. 292, Núm. 15, pp. 6255-6268
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Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS
Structure, Vol. 25, Núm. 7, pp. 1034-1044.e3
2016
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Molecular basis of membrane association by the phosphatidylinositol mannosyltransferase PimA enzyme from mycobacteria
Journal of Biological Chemistry, Vol. 291, Núm. 27, pp. 13955-13963
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Structural Basis of Glycogen Biosynthesis Regulation in Bacteria
Structure, Vol. 24, Núm. 9, pp. 1613-1622
2015
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A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase
Angewandte Chemie - International Edition, Vol. 54, Núm. 34, pp. 9898-9902
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Secondary structure reshuffling modulates glycosyltransferase function at the membrane
Nature Chemical Biology, Vol. 11, Núm. 1, pp. 16-18
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The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053
Journal of Biological Chemistry, Vol. 290, Núm. 52, pp. 31077-31089
2014
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Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis
ACS Chemical Biology, Vol. 9, Núm. 7, pp. 1567-1575
2013
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Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria
Journal of Biological Chemistry, Vol. 288, Núm. 41, pp. 29797-29808