Centro de Investigacion Biomedica en Red de Salud Mental-ko ikertzaileekin lankidetzan egindako argitalpenak (29)

2024

  1. Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling

    Science signaling, Vol. 17, Núm. 841, pp. eadi4747

  2. Effect of antipsychotic drugs on group II metabotropic glutamate receptor expression and epigenetic control in postmortem brains of schizophrenia subjects

    Translational Psychiatry, Vol. 14, Núm. 1

  3. G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

    Nature communications, Vol. 15, Núm. 1, pp. 4307

  4. Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain

    British Journal of Pharmacology

  5. The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls

    EMBO Molecular Medicine, Vol. 16, Núm. 4, pp. 755-783

2023

  1. 35S]GTPγS (Guanosine-5'-O-(γ-thio)triphosphate-[35S]) Binding Scintillation Proximity Assay Experiments in Postmortem Brain Tissue

    Methods in molecular biology (Clifton, N.J.), Vol. 2687, pp. 31-43

  2. Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5-HT2A Receptor Inverse Agonists

    Journal of Medicinal Chemistry, Vol. 66, Núm. 13, pp. 9057-9075

  3. Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects

    Molecular Neurobiology, Vol. 60, Núm. 8, pp. 4472-4487

  4. Selective inhibition of cannabinoid CB1 receptor-evoked signalling by the interacting protein GAP43

    Neuropharmacology, Vol. 240

2021

  1. Characterization of dopamine D2 receptor coupling to G proteins in postmortem brain of subjects with schizophrenia

    Pharmacological Reports, Vol. 73, Núm. 4, pp. 1136-1146

  2. Correction to: Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation (Pharmacological Reports, (2021), 73, 4, (1079-1095), 10.1007/s43440-021-00253-z)

    Pharmacological Reports

  3. Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation

    Pharmacological Reports, Vol. 73, Núm. 4, pp. 1079-1095

  4. Identification of bip as a cb1 receptor-interacting protein that fine-tunes cannabinoid signaling in the mouse brain

    Journal of Neuroscience, Vol. 41, Núm. 38, pp. 7924-7941

  5. Opposite alterations of 5­HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile

    Translational Psychiatry, Vol. 11, Núm. 1

  6. Serotonin 2A receptors and cannabinoids

    Progress in Brain Research (Elsevier B.V.), pp. 135-175

  7. α2A- and α2C-adrenoceptor expression and functionality in postmortem prefrontal cortex of schizophrenia subjects

    European Neuropsychopharmacology, Vol. 52, pp. 3-11

2020

  1. Pimavanserin exhibits serotonin 5-HT2A receptor inverse agonism for Gαi1- and neutral antagonism for Gαq/11-proteins in human brain cortex

    European Neuropsychopharmacology, Vol. 36, pp. 83-89

  2. Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia

    Frontiers in Pharmacology, Vol. 11

2019

  1. Therapeutic targeting of HER2–CB 2 R heteromers in HER2-positive breast cancer

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Núm. 9, pp. 3863-3872

  2. Chronic fluoxetine reverses the effects of chronic corticosterone treatment on α2-adrenoceptors in the rat frontal cortex but not locus coeruleus

    Neuropharmacology, Vol. 158