José Javier
Meana Martínez
Centro de Investigacion Biomedica en Red de Salud Mental
Madrid, EspañaPublications in collaboration with researchers from Centro de Investigacion Biomedica en Red de Salud Mental (83)
2024
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G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits
Nature communications, Vol. 15, Núm. 1, pp. 4307
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High number of mitochondrial DNA alterations in postmortem brain tissue of patients with schizophrenia compared to healthy controls
Psychiatry Research, Vol. 337
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Ligand bias and inverse agonism on 5-HT2A receptor-mediated modulation of G protein activity in post-mortem human brain
British Journal of Pharmacology
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Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome
Biomedicines, Vol. 12, Núm. 1
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Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia
Journal of Psychiatry and Neuroscience, Vol. 49, Núm. 1, pp. E35-E44
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Poly (I:C)-induced maternal immune activation generates impairment of reversal learning performance in offspring
Journal of Neurochemistry
2023
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Agonistic properties of a series of psychotropic drugs at 5-HT1A receptors in rat and human brain membranes determined by [35S]GTPγS binding assay
Pharmacological Reports, Vol. 75, Núm. 2, pp. 266-275
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Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5-HT2A Receptor Inverse Agonists
Journal of Medicinal Chemistry, Vol. 66, Núm. 13, pp. 9057-9075
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Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia
International Journal of Molecular Sciences, Vol. 24, Núm. 7
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Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects
Molecular Neurobiology, Vol. 60, Núm. 8, pp. 4472-4487
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Maternal Immune Activation Induces Cortical Catecholaminergic Hypofunction and Cognitive Impairments in Offspring
Journal of Neuroimmune Pharmacology, Vol. 18, Núm. 3, pp. 348-365
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Serotonin 5-HT2A receptors in schizophrenia: Reflexions on an unfinished story
European Neuropsychopharmacology
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The Role of α-Synuclein in the Regulation of Serotonin System: Physiological and Pathological Features
Biomedicines, Vol. 11, Núm. 2
2022
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Cannabis use selectively modulates circulating biomarkers in the blood of schizophrenia patients
Addiction Biology, Vol. 27, Núm. 6
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High S100B Levels Predict Antidepressant Response in Patients With Major Depression Even When Considering Inflammatory and Metabolic Markers
International Journal of Neuropsychopharmacology, Vol. 25, Núm. 6, pp. 468-478
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Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response
Biomedicine and Pharmacotherapy, Vol. 154
2021
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5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated activation of Gαq/11 in postmortem dorsolateral prefrontal cortex of opiate addicts
Pharmacological Reports, Vol. 73, Núm. 4, pp. 1155-1163
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5-HT2A receptor-mediated Gαq/11 activation in psychiatric disorders: A postmortem study
World Journal of Biological Psychiatry, Vol. 22, Núm. 7, pp. 505-515
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Characterization of dopamine D2 receptor coupling to G proteins in postmortem brain of subjects with schizophrenia
Pharmacological Reports, Vol. 73, Núm. 4, pp. 1136-1146
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Correction to: Functional approaches to the study of G-protein-coupled receptors in postmortem brain tissue: [35S]GTPγS binding assays combined with immunoprecipitation (Pharmacological Reports, (2021), 73, 4, (1079-1095), 10.1007/s43440-021-00253-z)
Pharmacological Reports