Publicaciones en colaboración con investigadores/as de Universidad del País Vasco/Euskal Herriko Unibertsitatea (15)

2024

  1. A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection

    Nature Biotechnology

  2. Cryo-EM structure of the Rev1–Polζ holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis

    Nature Structural and Molecular Biology, Vol. 31, Núm. 9, pp. 1394-1403

2023

  1. Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane

    Nature Communications, Vol. 14, Núm. 1

2021

  1. Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope

    Scientific Reports, Vol. 11, Núm. 1

2020

  1. Presenilin1 familial Alzheimer disease mutants inactivate EFNB1-and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-Aspartate receptor

    Brain Communications, Vol. 2, Núm. 2

  2. Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin

    Nature Communications, Vol. 11, Núm. 1

  3. Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis

    Nature Structural and Molecular Biology, Vol. 27, Núm. 10, pp. 913-924

  4. Substrate interaction inhibits γ-secretase production of amyloid-β peptides

    Chemical Communications, Vol. 56, Núm. 17, pp. 2578-2581

  5. Substrate–Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype

    Frontiers in Molecular Neuroscience, Vol. 13

2019

  1. Vitamin B 12 modulates Parkinson’s disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

    Cell Research, Vol. 29, Núm. 4, pp. 313-329

  2. CD46 facilitates entry and dissemination of human cytomegalovirus

    Nature Communications, Vol. 10, Núm. 1

  3. Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme

    Nature Structural and Molecular Biology, Vol. 26, Núm. 10, pp. 955-962

2018

  1. Coupled Transmembrane Substrate Docking and Helical Unwinding in Intramembrane Proteolysis of Amyloid Precursor Protein

    Scientific Reports, Vol. 8, Núm. 1

  2. Design and validation of an open-source modular Microplate Photoirradiation System for high-Throughput photobiology experiments

    PLoS ONE, Vol. 13, Núm. 10

  3. Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis

    Biophysical Journal, Vol. 114, Núm. 7, pp. 1579-1589