Izaskun
Buendía Abaitua
Postdoctoral researcher
Manuela
García López
Publicaciones en las que colabora con Manuela García López (28)
2020
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Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease
Antioxidants, Vol. 9, Núm. 8, pp. 1-20
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Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization
Pharmacological Research, Vol. 152
2019
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Neuroprotective effects of EpoL against oxidative stress induced by soluble oligomers of Aβ peptide
Redox Biology, Vol. 24
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Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
Journal of Pineal Research, Vol. 67, Núm. 1
2018
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The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities
Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182
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Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy
Redox Biology, Vol. 18, pp. 173-180
2017
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Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"
ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210
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ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels
Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359
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Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease
Scientific Reports, Vol. 7
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Heme-Oxygenase i and PCG-1α Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987
Antioxidants and Redox Signaling, Vol. 27, Núm. 2, pp. 93-105
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ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia
ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81
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Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Redox Biology, Vol. 12, pp. 1040-1051
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NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage
Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 46, pp. 12315-12320
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Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices
Neuropharmacology, Vol. 116, pp. 110-121
2016
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Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice
Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3030-3045
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Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3338-3348
2015
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Agmatine Induces Nrf2 and Protects Against Corticosterone Effects in Hippocampal Neuronal Cell Line
Molecular Neurobiology, Vol. 51, Núm. 3, pp. 1504-1519
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Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction
Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 473-481
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Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 463-472
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CALHM1 and its polymorphism P86L differentially control Ca2+ homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β
Aging Cell, Vol. 14, Núm. 6, pp. 1094-1102