Publicaciones en colaboración con investigadores/as de University of Oxford (27)

2024

  1. Advanced Methods In Parkinson’s Disease Research

    Journal of Visualized Experiments

  2. BirthSeq, a new method to isolate and analyze dated cells in different vertebrates

    Development (Cambridge), Vol. 151, Núm. 13

  3. Crosstalk between mitochondria–ER contact sites and the apoptotic machinery as a novel health meter

    Trends in Cell Biology

  4. Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

    npj Parkinson's Disease, Vol. 10, Núm. 1

  5. Tau depletion in human neurons mitigates Aβ-driven toxicity

    Molecular Psychiatry, Vol. 29, Núm. 7, pp. 2009-2020

2023

  1. Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons

    iScience, Vol. 26, Núm. 7

2021

  1. LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

    EMBO Molecular Medicine, Vol. 13, Núm. 9

  2. REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing bac-transgenic mouse model

    Journal of Neuroscience, Vol. 41, Núm. 16, pp. 3731-3746

  3. Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol

    Frontiers in Cellular Neuroscience, Vol. 15

  4. Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease

    Acta Neuropathologica Communications, Vol. 9, Núm. 1

2020

  1. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease

    Nature Communications, Vol. 11, Núm. 1

  2. GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model

    Nature Communications, Vol. 11, Núm. 1

  3. Transgenic mice expressing human a-synuclein in noradrenergic neurons develop locus ceruleus pathology and nonmotor features of parkinson's disease

    Journal of Neuroscience, Vol. 40, Núm. 39, pp. 7559-7576

2019

  1. Alpha-synuclein proximity ligation assay (AS-PLA) in brain sections to probe for alpha-synuclein oligomers

    Methods in Molecular Biology (Humana Press Inc.), pp. 69-76

  2. Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons

    Human Molecular Genetics, Vol. 28, Núm. 12, pp. 2001-2013

  3. Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior

    Cell Reports, Vol. 29, Núm. 4, pp. 920-931.e7

  4. Selective vulnerability in α-synucleinopathies

    Acta Neuropathologica, Vol. 138, Núm. 5, pp. 681-704

  5. Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

    Frontiers in Molecular Neuroscience, Vol. 12

2018

  1. Detection of alpha-synuclein conformational variants from gastro-intestinal biopsy tissue as a potential biomarker for Parkinson's disease

    Neuropathology and Applied Neurobiology, Vol. 44, Núm. 7, pp. 722-736

2017

  1. Alpha-synuclein oligomers: a new hope

    Acta Neuropathologica, Vol. 134, Núm. 6, pp. 819-838