Publicaciones en colaboración con investigadores/as de University of Oxford (26)

2024

  1. Advanced Methods In Parkinson’s Disease Research

    Journal of Visualized Experiments

  2. BirthSeq, a new method to isolate and analyze dated cells in different vertebrates

    Development (Cambridge), Vol. 151, Núm. 13

  3. Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

    npj Parkinson's Disease, Vol. 10, Núm. 1

  4. Tau depletion in human neurons mitigates Aβ-driven toxicity

    Molecular Psychiatry, Vol. 29, Núm. 7, pp. 2009-2020

2023

  1. Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons

    iScience, Vol. 26, Núm. 7

2021

  1. LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

    EMBO Molecular Medicine, Vol. 13, Núm. 9

  2. REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing bac-transgenic mouse model

    Journal of Neuroscience, Vol. 41, Núm. 16, pp. 3731-3746

  3. Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol

    Frontiers in Cellular Neuroscience, Vol. 15

  4. Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease

    Acta Neuropathologica Communications, Vol. 9, Núm. 1

2020

  1. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease

    Nature Communications, Vol. 11, Núm. 1

  2. GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model

    Nature Communications, Vol. 11, Núm. 1

  3. Transgenic mice expressing human a-synuclein in noradrenergic neurons develop locus ceruleus pathology and nonmotor features of parkinson's disease

    Journal of Neuroscience, Vol. 40, Núm. 39, pp. 7559-7576

2019

  1. Alpha-synuclein proximity ligation assay (AS-PLA) in brain sections to probe for alpha-synuclein oligomers

    Methods in Molecular Biology (Humana Press Inc.), pp. 69-76

  2. Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons

    Human Molecular Genetics, Vol. 28, Núm. 12, pp. 2001-2013

  3. Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior

    Cell Reports, Vol. 29, Núm. 4, pp. 920-931.e7

  4. Selective vulnerability in α-synucleinopathies

    Acta Neuropathologica, Vol. 138, Núm. 5, pp. 681-704

  5. Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

    Frontiers in Molecular Neuroscience, Vol. 12

2018

  1. Detection of alpha-synuclein conformational variants from gastro-intestinal biopsy tissue as a potential biomarker for Parkinson's disease

    Neuropathology and Applied Neurobiology, Vol. 44, Núm. 7, pp. 722-736

2017

  1. Alpha-synuclein oligomers: a new hope

    Acta Neuropathologica, Vol. 134, Núm. 6, pp. 819-838

  2. Identification of Noncanonical Wnt Receptors Required for Wnt-3a-Induced Early Differentiation of Human Neural Stem Cells

    Molecular Neurobiology, Vol. 54, Núm. 8, pp. 6213-6224