Publications (24) Amaia Arranz Mendiguren publications

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2025

  1. Astrocytes as Therapeutic Targets in Neurodegenerative Disorders

    The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 45, Núm. 46

2024

  1. APOE from astrocytes restores Alzheimer’s Aβ-pathology and DAM-like responses in APOE deficient microglia

    EMBO Molecular Medicine, Vol. 16, Núm. 12, pp. 3113-3141

  2. Centenarian hippocampus displays high levels of astrocytic metallothioneins

    Aging Cell, Vol. 23, Núm. 8

2023

  1. A neuron-specific interaction between Alzheimer's disease risk factors SORL1, APOE, and CLU

    Cell Reports

  2. MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease

    Science (New York, N.Y.), Vol. 381, Núm. 6663, pp. 1176-1182

  3. hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer’s disease and potential therapeutics

    Molecular Neurodegeneration

2022

  1. Evolution of neuroglia

    Annals of the New York Academy of Sciences, Vol. 1518, Núm. 1, pp. 120-130

2021

  1. Astrocytes in Alzheimer's Disease: Pathological Significance and Molecular Pathways

    Cells, Vol. 10, Núm. 3

  2. Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques

    Molecular Neurodegeneration, Vol. 16, Núm. 1

2019

  1. PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Núm. 1, pp. 277-286

  2. Stem-cell-derived human microglia transplanted in mouse brain to study human disease

    Nature Neuroscience, Vol. 22, Núm. 12, pp. 2111-2116

  3. The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

    The Lancet Neurology, Vol. 18, Núm. 4, pp. 406-414

2017

  1. Brain extracellular space, hyaluronan, and the prevention of epileptic seizures

    Reviews in the Neurosciences, Vol. 28, Núm. 8, pp. 869-892

  2. Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity (PLoS ONE) (2017) 12:2 (e0171968) DOI: 10.1371/journal.pone.0171968)

    PLoS ONE

  3. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

    Neuron, Vol. 93, Núm. 5, pp. 1066-1081.e8

  4. PLD3 gene and processing of APP

    Nature

  5. Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity

    PLoS ONE, Vol. 12, Núm. 2

  6. Tetraspanin 6: A pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments

    Molecular Neurodegeneration, Vol. 12, Núm. 1

2015

  1. LRRK2 functions in synaptic vesicle endocytosis through a kinasedependent mechanism

    Journal of Cell Science, Vol. 128, Núm. 3, pp. 541-552

2014

  1. Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space

    Journal of Neuroscience, Vol. 34, Núm. 18, pp. 6164-6176