Publicaciones en colaboración con investigadores/as de Universidad del País Vasco/Euskal Herriko Unibertsitatea (38)

2024

  1. Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided strategy

    Biomedicine and Pharmacotherapy, Vol. 174

  2. MLe-KCNQ2: An Artificial Intelligence Model for the Prognosis of Missense KCNQ2 Gene Variants

    International Journal of Molecular Sciences, Vol. 25, Núm. 5

2023

  1. Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel

    Journal of Biological Chemistry, Vol. 299, Núm. 2

2022

  1. Gure bihotzeko kalmodulina

    Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 42, pp. 173-191

  2. Microglia-Mediated Inflammation and Neural Stem Cell Differentiation in Alzheimer’s Disease: Possible Therapeutic Role of KV1.3 Channel Blockade

    Frontiers in Cellular Neuroscience, Vol. 16

2021

  1. An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel

    BMC Biology, Vol. 19, Núm. 1

  2. Do calmodulin binding IQ motifs have built-in capping domains?

    Protein Science, Vol. 30, Núm. 10, pp. 2029-2041

  3. KV7.2 kanala: estruktura, erregulazioa eta kitzikagarritasun neuronalean duen ekintza

    Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 39, pp. 37-60

2020

  1. Atomistic insights of calmodulin gating of complete ion channels

    International Journal of Molecular Sciences, Vol. 21, Núm. 4

  2. Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

    Cell Death and Disease, Vol. 11, Núm. 12

  3. Novel dominant kcnq2 exon 7 partial in-frame duplication in a complex epileptic and neurodevelopmental delay syndrome

    International Journal of Molecular Sciences, Vol. 21, Núm. 12, pp. 1-11

2019

  1. Homomeric Kv7.2 current suppression is a common feature in KCNQ2 epileptic encephalopathy

    Epilepsia, Vol. 60, Núm. 1, pp. 139-148

  2. The crossroad of ion channels and Calmodulin in disease

    International Journal of Molecular Sciences, Vol. 20, Núm. 2

2018

  1. Correction: Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel (Proceedings of the National Academy of Sciences of the United States of America (2018) 115 (2395-2400) DOI: 10.1073/pnas.1800235115)

    Proceedings of the National Academy of Sciences of the United States of America

  2. Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Núm. 10, pp. 2395-2400

2017

  1. Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin

    Frontiers in Molecular Neuroscience, Vol. 10

  2. Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes

    Scientific Reports, Vol. 7

2016

  1. Ubiquitin-specific protease 36 (USP36) controls neuronal precursor cell-expressed developmentally down-regulated 4-2 (Nedd4-2) actions over the neurotrophin receptor TrkA and potassium voltage-gated channels 7.2/3 (kv7.2/3)

    Journal of Biological Chemistry, Vol. 291, Núm. 36, pp. 19132-19145

2015

  1. An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels

    Journal of Cell Science, Vol. 128, Núm. 16, pp. 3155-3163

  2. Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1852, Núm. 9, pp. 1856-1866