Plegamiento defectuoso de proteínas y enfermedad
Publicaciones (312) Publicaciones en las que ha participado algún/a investigador/a
2024
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A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion
Journal of the American Chemical Society
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Author Correction: The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70 (Nature Communications, (2023), 14, 1, (5436), 10.1038/s41467-023-41150-8)
Nature Communications
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Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity
Molecular Psychiatry, Vol. 29, Núm. 3, pp. 686-703
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Pseudophosphorylation of single residues of the J-domain of DNAJA2 regulates the holding/folding balance of the Hsc70 system
Protein Science, Vol. 33, Núm. 8
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The unreasonable effectiveness of equilibrium gene regulation through the cell cycle
Cell Systems, Vol. 15, Núm. 7, pp. 639-648.e2
2023
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Correction: Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology (Translational Neurodegeneration, (2022), 11, 1, (58), 10.1186/s40035-022-00329-7)
Translational Neurodegeneration
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Dynamics-informed deconvolutional neural networks for super-resolution identification of regime changes in epidemiological time series
Science advances, Vol. 9, Núm. 28, pp. eadf0673
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Multi-landmark alignment of genomic signals reveals conserved expression patterns across transcription start sites
Scientific reports, Vol. 13, Núm. 1, pp. 10835
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Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane
Nature Communications, Vol. 14, Núm. 1
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The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70
Nature communications, Vol. 14, Núm. 1, pp. 5436
2022
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Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2
Journal of Molecular Biology, Vol. 434, Núm. 22
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Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 41
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Robustness of DNA looping across multiple cell divisions in individual bacteria
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 33
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Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism
Brain, Vol. 145, Núm. 6, pp. 2092-2107
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Targeting the overexpressed mitochondrial protein VDAC1 in a mouse model of Alzheimer’s disease protects against mitochondrial dysfunction and mitigates brain pathology
Translational Neurodegeneration, Vol. 11, Núm. 1
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The P. aeruginosa effector Tse5 forms membrane pores disrupting the membrane potential of intoxicated bacteria
Communications Biology, Vol. 5, Núm. 1
2021
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Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure
Frontiers in Synaptic Neuroscience, Vol. 13
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All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 36
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Altered cerebellar response to somatosensory stimuli in the Cntnap2 mouse model of autism
eNeuro, Vol. 8, Núm. 5
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Ascertaining the initiation of epidemic resurgences: An application to the COVID-19 second surges in Europe and the Northeast United States
Royal Society Open Science, Vol. 8, Núm. 10