Plegamiento defectuoso de proteínas y enfermedad
Universidad del País Vasco/Euskal Herriko Unibertsitatea
Lejona, EspañaPublicaciones en colaboración con investigadores/as de Universidad del País Vasco/Euskal Herriko Unibertsitatea (151)
2024
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A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion
Journal of the American Chemical Society
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Author Correction: The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70 (Nature Communications, (2023), 14, 1, (5436), 10.1038/s41467-023-41150-8)
Nature Communications
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Pseudophosphorylation of single residues of the J-domain of DNAJA2 regulates the holding/folding balance of the Hsc70 system
Protein Science, Vol. 33, Núm. 8
2023
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Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane
Nature Communications, Vol. 14, Núm. 1
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The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70
Nature communications, Vol. 14, Núm. 1, pp. 5436
2022
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Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2
Journal of Molecular Biology, Vol. 434, Núm. 22
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Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 41
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Robustness of DNA looping across multiple cell divisions in individual bacteria
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 33
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Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism
Brain, Vol. 145, Núm. 6, pp. 2092-2107
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The P. aeruginosa effector Tse5 forms membrane pores disrupting the membrane potential of intoxicated bacteria
Communications Biology, Vol. 5, Núm. 1
2021
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Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure
Frontiers in Synaptic Neuroscience, Vol. 13
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All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 36
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Altered cerebellar response to somatosensory stimuli in the Cntnap2 mouse model of autism
eNeuro, Vol. 8, Núm. 5
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Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison
Frontiers in Microbiology, Vol. 12
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FORTIS: a live-cell assay to monitor AMPA receptors using pH-sensitive fluorescence tags
Translational Psychiatry, Vol. 11, Núm. 1
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Inhibition of the human hsc70 system by small ligands as a potential anticancer approach
Cancers, Vol. 13, Núm. 12
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Truncation‐driven lateral association of α‐synuclein hinders amyloid clearance by the Hsp70‐based disaggregase
International Journal of Molecular Sciences, Vol. 22, Núm. 23
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Unzipping the secrets of amyloid disassembly by the human disaggregase
Cells, Vol. 10, Núm. 10
2020
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Corrigendum to: -PTEN activity defines an axis for plasticity at cortico-amygdala synapses and influences social behavior
Cerebral cortex (New York, N.Y. : 1991)
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945