Plegamiento defectuoso de proteínas y enfermedad
Centro de Investigación Cooperativa en Biotecnología
Zamudio, EspañaPublicaciones en colaboración con investigadores/as de Centro de Investigación Cooperativa en Biotecnología (18)
2024
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Pseudophosphorylation of single residues of the J-domain of DNAJA2 regulates the holding/folding balance of the Hsc70 system
Protein Science, Vol. 33, Núm. 8
2022
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Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2
Journal of Molecular Biology, Vol. 434, Núm. 22
2021
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Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells
Nature Microbiology, Vol. 6, Núm. 9, pp. 1199-1210
2020
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8
Journal of Structural Biology, Vol. 212, Núm. 3
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The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM
Current Research in Structural Biology, Vol. 2, pp. 89-103
2019
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Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases
Methods in Enzymology (Academic Press Inc.), pp. 261-279
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Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain
Journal of Molecular Biology, Vol. 431, Núm. 2, pp. 444-461
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Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC
Journal of Biological Chemistry, Vol. 294, Núm. 50, pp. 19066-19080
2018
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The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria
ACS Chemical Biology, Vol. 13, Núm. 1, pp. 131-140
2017
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Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS
Structure, Vol. 25, Núm. 7, pp. 1034-1044.e3
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Structural Snapshots of α-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases
Angewandte Chemie - International Edition, Vol. 56, Núm. 47, pp. 14853-14857
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Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1862, Núm. 11, pp. 1355-1367
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The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis
Journal of Biological Chemistry, Vol. 292, Núm. 32, pp. 13097-13110
2016
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Structural Basis of Glycogen Biosynthesis Regulation in Bacteria
Structure, Vol. 24, Núm. 9, pp. 1613-1622
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Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
Nature Communications, Vol. 7
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The conformational plasticity of glycosyltransferases
Current Opinion in Structural Biology, Vol. 40, pp. 23-32
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TssA forms a gp6-like ring attached to the type VI secretion sheath
EMBO Journal, Vol. 35, Núm. 15, pp. 1613-1627