Publicaciones en las que colabora con Diego Marcelo Guérin Aguilar (22)
2020
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM
Current Research in Structural Biology, Vol. 2, pp. 89-103
2019
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Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases
Methods in Enzymology (Academic Press Inc.), pp. 261-279
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Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain
Journal of Molecular Biology, Vol. 431, Núm. 2, pp. 444-461
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Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC
Journal of Biological Chemistry, Vol. 294, Núm. 50, pp. 19066-19080
2018
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The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria
ACS Chemical Biology, Vol. 13, Núm. 1, pp. 131-140
2017
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Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS
Structure, Vol. 25, Núm. 7, pp. 1034-1044.e3
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Structural Snapshots of α-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases
Angewandte Chemie - International Edition, Vol. 56, Núm. 47, pp. 14853-14857
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Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1862, Núm. 11, pp. 1355-1367
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The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis
Journal of Biological Chemistry, Vol. 292, Núm. 32, pp. 13097-13110
2016
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Structural Basis of Glycogen Biosynthesis Regulation in Bacteria
Structure, Vol. 24, Núm. 9, pp. 1613-1622
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Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
Nature Communications, Vol. 7
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The conformational plasticity of glycosyltransferases
Current Opinion in Structural Biology, Vol. 40, pp. 23-32
2015
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A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase
Angewandte Chemie - International Edition, Vol. 54, Núm. 34, pp. 9898-9902
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Secondary structure reshuffling modulates glycosyltransferase function at the membrane
Nature Chemical Biology, Vol. 11, Núm. 1, pp. 16-18
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The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053
Journal of Biological Chemistry, Vol. 290, Núm. 52, pp. 31077-31089
2014
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Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis
ACS Chemical Biology, Vol. 9, Núm. 7, pp. 1567-1575
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Structural basis of chitin oligosaccharide deacetylation
Angewandte Chemie - International Edition, Vol. 53, Núm. 27, pp. 6882-6887
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Structure-function relationships of membrane-associated GT-B glycosyltransferases
Glycobiology, Vol. 24, Núm. 2, pp. 108-124
2013
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Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria
Journal of Biological Chemistry, Vol. 288, Núm. 41, pp. 29797-29808