Laboratory of Local Translation in Neurons and Glia
Publications (23)
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2025
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Astrocyte-secreted factors modulate synaptic protein synthesis as revealed by puromycin labeling of isolated synaptosomes
Frontiers in Molecular Neuroscience, Vol. 18
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Disruption of hnRNP A2-mediated RNA dynamics by amyloid-β drives MBP increase in Alzheimer’s disease
Cellular and Molecular Life Sciences, Vol. 82, Núm. 1
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RNA-binding protein IMP1/ZBP1 directs local translation in microglial processes to regulate motility and phagocytosis during inflammation
PLoS biology, Vol. 23, Núm. 11, pp. e3003463
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Vesicular Rps6 Released by Astrocytes in an Experimental Model of AD Regulates Local Translation and Enhances Synaptic Integrity in Neurones
Journal of Extracellular Vesicles, Vol. 14, Núm. 12
2024
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Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis
Science Advances , Vol. 10, Núm. 42
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Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
npj Parkinson's Disease, Vol. 10, Núm. 1
2023
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CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer’s disease gene expression linked to neuropathology
Science Advances, Vol. 9, Núm. 9
2021
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Corrigendum: Object-Based Analyses in FIJI/ImageJ to Measure Local RNA Translation Sites in Neurites in Response to Aβ1-42 Oligomers (Front. Neurosci., (2020), 14, (547), 10.3389/fnins.2020.00547)
Frontiers in Neuroscience
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Local Translation in Nervous System Pathologies
Frontiers in Integrative Neuroscience, Vol. 15
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RNA Localization and Local Translation in Glia in Neurological and Neurodegenerative Diseases: Lessons from Neurons
Cells, Vol. 10, Núm. 3
2020
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Object-Based Analyses in FIJI/ImageJ to Measure Local RNA Translation Sites in Neurites in Response to Aβ1-42 Oligomers
Frontiers in Neuroscience, Vol. 14
2019
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Aβ oligomers promote oligodendrocyte differentiation and maturation via integrin β1 and Fyn kinase signaling
Cell Death and Disease, Vol. 10, Núm. 6
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RAG-2 deficiency results in fewer phosphorylated histone H2AX foci, but increased retinal ganglion cell death and altered axonal growth
Scientific Reports, Vol. 9, Núm. 1
2018
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Aβ 1–42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons
EMBO Reports, Vol. 19, Núm. 7
2017
2016
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Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina
Scientific Reports, Vol. 6
2015
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Detection of axonally localized mRNAs in brain sections using high-resolution in situ hybridization
Journal of Visualized Experiments, Vol. 2015, Núm. 100
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Stereotaxic infusion of oligomeric amyloid-beta into the mouse hippocampus
Journal of Visualized Experiments, Vol. 2015, Núm. 100
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Targeting Axonal Protein Synthesis in Neuroregeneration and Degeneration
Neurotherapeutics, Vol. 12, Núm. 1, pp. 57-65
2014
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Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions
Cell, Vol. 158, Núm. 5, pp. 1159-1172