Aterosklerosiaren fisiopatologiadisfuntzio endotelialetik plakaren hausturara
- Jebari Benslaiman, Shifa 1
- Larrea Sebal, Asier 2
- B.Uribe, Kepa 1
- Benito Vicente, Asier 1
- Galicia García, Unai 1
- San José Urteaga, Ane 1
- Martín, César 1
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1
Universidad del País Vasco/Euskal Herriko Unibertsitatea
info
Universidad del País Vasco/Euskal Herriko Unibertsitatea
Lejona, España
- 2 Biofisika Institutua (CSIC-EHU)
ISSN: 2530-9412
Año de publicación: 2024
Volumen: 8
Número: 1
Páginas: 119-132
Tipo: Artículo
Otras publicaciones en: Osagaiz: osasun-zientzien aldizkaria
Resumen
Atherosclerosis, the main risk factor for cardiovascular disease, is initiated by endothelium activation and followed by a cascade of events such as accumulation of lipids, fibrous elements and calcification. These processes trigger atheroma plaque formation and activation of inflammatory pathways. These processes along with the resulting vessel narrowing could promote cardiovascular clinical complications. This review summarizes the different stages of atherosclerosis development, ranging from endothelial dysfunction to plaque rupture, along with current treatment of the disease.
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