Psilozibinaren administrazio akutuaren eraginen ebaluazioa garun kortexean serotonina, noradrenalina eta dopamina mailak neurtuzgarun-mikrodialisiaren bidez burututako ikerlana esna dauden saguetan

  1. Nerea Martínez Alvárez 1
  2. Ines Erkizia Santamaria
  3. Igor Horrillo Furundarena
  4. José Javier Meana Martínez
  5. Jorge E. Ortega Calvo
  1. 1 Universidad del País Vasco/Euskal Herriko Unibertsitatea
    info

    Universidad del País Vasco/Euskal Herriko Unibertsitatea

    Lejona, España

    ROR https://ror.org/000xsnr85

Libro:
Osasun zientziak: V. Ikergazte Nazioarteko Ikerteta Euskaraz. 2023eko maitzaren 17, 18 eta 19 Donostia, Euskal Herria.
  1. Olatz Arbelaitz Gallego (ed. lit.)
  2. Ainhoa Latatu (ed. lit.)
  3. Elixabete Pérez Gaztelu (ed. lit.)

Editorial: Udako Euskal Unibertsitatea, UEU = Universidad Vasca de Verano

ISBN: 978-84-8438-862-3,  978-84-8438-866-1

Año de publicación: 2023

Páginas: 115-122

Congreso: Ikergazte. Nazioarteko Ikerketa Euskaraz (5. 2023. Donostia)

Tipo: Aportación congreso

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Resumen

Psilocybin is a natural hallucinogenic compound that has been shown to have potential antidepressant ejfects. However, the mechanism of action is largely unknown. Therefore, in this study, we investigated the ejfect of psilocybin on the frontal cortex monoamine extracellular concentrations using in vivo brain microdialysis technique. At the dose used (] mg/kg), no significant changes in monoamine concentration were observed. This leads to the conclusion that the antidepressant mechanism of action of psilocybin, unlike current antidepressants, does not primarily involve an increase in extracellular monoamines infrontal cortex.

Fuente de los datos: Dialnet