Sare metal-organikoetan oinarritutako farmakoen liberazio sistemakbiomolekulak atxikitzeko funtzionalizazio-estrategiak

  1. Celaya Azcoaga, Leire 1
  2. Fidalgo-Marijuan, Arkaitz
  3. Fernández de Luis, Roberto
  1. 1 Basque Center for Materials, Applications and Nanostructures (BCMaterials) eta Euskal Herriko Unibertsitatea (UPV/EHU).
Journal:
Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria

ISSN: 0214-9001

Year of publication: 2022

Issue: 42

Pages: 227-239

Type: Article

DOI: 10.1387/EKAIA.22809 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria

Abstract

Drug delivery systems (DDSs) based on metal-organic frameworks (MOFs) overcome the limits shown by conventionally used drug delivery systems. Due to their hybrid inorganic-organic nature, MOFs are able to combine the advantages shown by inorganic and organic based conventional DDSs, while minimising their drawbacks. In this work, after explaining the general characteristics that DDS systems must fullfil, the key properties of MOFs for their use as DDSs are discussed. More specifically, the five most used functionalization strategies to achieve a controled incorporation and/or release of biomolecules within MOF structures will be explained.

Data source: Dialnet