Perfil de deterioro cognitivo en personas con esquizofrenia paranoide:Estudio breve en población peruana

  1. Jonathan A. Zegarra Valdivia 1
  2. Brenda Chino Vilca 1
  1. 1 Universidad Nacional de San Agustín de Arequipa, Perú
Zeitschrift:
Cuadernos de Neuropsicología

ISSN: 0718-4123

Datum der Publikation: 2020

Ausgabe: 14

Nummer: 3

Seiten: 121-129

Art: Artikel

DIALNET GOOGLE SCHOLAR lock_openOpen Access editor

Andere Publikationen in: Cuadernos de Neuropsicología

Zusammenfassung

A esquizofrenia possui uma ampla carga de adoecimento, alteração social e funcional, e uma pobre resposta terapêutica. Seus efeitos se relacionam com desordens significativas nos processos cognitivos, no entanto, muitas vezes não são devidamente avaliadas nem possuem o acompanhamento adequado. Objetivos: Caracterizar o perfil de deterioração cognitiva de pessoas com esquizofrenia paranoide. Material e métodos: Foi comparado o perfil de sujeitos diagnosticados com esquizofrenia paranoide segundo o DSM-IV-TR, ao de sujeitos controles pareados por idade sexo, utilizando uma amostra não probabilística e intencional. Foi realizada a estatística Paramétrica (T de Student) e Não paramétrica (U de Mann Whitney), assim como a Análise de Regressão Linear e Correlação de Pearson. Resultados: Foram encontradas diferenças estatisticamente significativas entre os perfis cognitivos do grupo clínico e controle em distintos processos específicos (Orientação, Memória, Fluidez Verbal, Lenguaje, Habilidade visual-espacial). Conclusões: O ACE-R mostra uma confiabilidade adequada e sua utilização para a avaliação de processos cognitivos na esquizofrenia é de grande utilidade.

Bibliographische Referenzen

  • Aich, T. K., Mahato, A., & Subedi, S. (2017). Cognitive Impairment in Schizophrenia: Current Perspective. Journal of Psychiatrists’ Association of Nepal, 5(1), 5–13. https://doi.org/10.3126/jpan.v5i1.18324
  • Baier, B., Karnath, H.-O., Dieterich, M., Birklein, F., Heinze, C., & Müller, N. G. (2010). Keeping memory clear and stable--the contribution of human basal ganglia and prefrontal cortex to working memory. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 30(29), 9788–9792.
  • Bell, M., Fiszdon, J., Greig, T., Wexler, B., & Bryson, G. (2007). Neurocognitive enhancement therapy with work therapy in schizophrenia: 6-month follow-up of neuropsychological performance. The Journal of Rehabilitation Research and Development, 44(5), 761.
  • Bell, M., Zito, W., Greig, T., & Wexler, B. E. (2008). Neurocognitive Enhancement Therapy and Competitive Employment in Schizophrenia: Effects on Clients with Poor Community Functioning. American Journal of Psychiatric Rehabilitation, 11(2), 109–122.
  • Brüne, M. (2005). “Theory of mind” in schizophrenia: A review of the literature. Schizophrenia Bulletin.
  • Cavieres F., A., & Valdebenito V., M. (2005). Funcionamiento cognitivo y calidad de vida en la esquizofrenia. Revista Chilena de NeuroPsiquiatría, 43(2), 97–108. https://doi.org/10.4067/S0717-92272005000200003
  • Fatemi, S. H. (2010). Clinical Handbook of Schizophrenia. The Journal of Clinical Psychiatry, 71(07), 962.
  • Fisekovic, S., Memic, A., & Pasalic, A. (2012). Correlation between MoCA and mmse for the assessment of cognition in schizophrenia. Acta Informatica Medica, 20(3), 186–189.
  • Gkintoni, E., Pallis, E. G., Bitsios, P., & Giakoumaki, S. G. (2017). Neurocognitive performance, psychopathology and social functioning in individuals at high risk for schizophrenia or psychotic bipolar disorder. Journal of Affective Disorders, 208(June 2016), 512–520.
  • Gliem, J. A., & Gliem, R. R. (2003). Calculating, Interpreting, and Reporting Cronbach’s Alpha Reliability Coefficient for Likert-Type Scales, (1992), 82–88. https://doi.org/10.1109/PROC.1975.9792
  • Green, M. F., Kern, R. S., & Heaton, R. K. (2004). Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for
  • Hernández-Sampieri, R., Fernández-Collado, C., Baptista, L. (2010). Metodología de la Investigación.
  • Herrera-Pérez, E., Custodio, N., Lira, D., Montesinos, R., & Bendezu, L. (2013). Validity of Addenbrooke’s Cognitive Examination to Discriminate between Incipient Dementia and Depression in Elderly Patients of a Private Clinic in Lima, Peru. Dementia and Geriatric Cognitive Disorders Extra, 3(1), 333–341.
  • Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The Positive and Negative Syndrome Scale for schizophrenia. Schizophr Bull., 13(2), 261–276. https://doi.org/10.1093/schbul/13.2.261
  • Keefe, R. S. E. (2008). Should cognitive impairment be included in the diagnostic criteria for schizophrenia? World Psychiatry, 7(1), 22–28.
  • Kontis, D., Theochari, E., Andreopoulou, A., Vassilouli, S., Siettou, E., Kouloumbi, M., … Tsaltas, E. (2018). A Cognitive Rehabilitation Program for Psychoses : Origins , Development and Perspectives, 25– 37.
  • Liang, S., Deng, W., Wang, Q., Ma, X., Li, M., Brown, M. R. G., … Li, T. (2016). Performance of Verbal Fluency as an Endophenotype in Patients with Familial versus Sporadic Schizophrenia and Their Parents. Scientific Reports, 6(August), 1–10. https://doi.org/10.1038/srep32597
  • Matiás-Guiu, J. A., Valles-Salgado, M., Rognoni, T., Hamre-Gil, F., MorenoRamos, T., & Matiás-Guiu, J. (2017). Comparative Diagnostic Accuracy of the ACE-III, MIS, MMSE, MoCA, and RUDAS for Screening of Alzheimer Disease. Dementia and Geriatric Cognitive Disorders, 43(5– 6), 237–246. https://doi.org/10.1159/000469658
  • Montero, I., & León, O. G. (2007). A guide for naming research studies in Psychology. International Journal of Clinical and Health Psychology, 7(3), 847–862.
  • Müller, D. R., & Roder, V. (2010). Integrated psychological therapy and integrated neurocognitive therapy. In Neurocognition and Social Cognition in Schizophrenia Patients: Basic Concepts and Treatment (Vol. 177, pp. 118–144). https://doi.org/10.1159/000284383
  • Ojeda, N., Peña, J., Bengoetxea, E., García, A., Sánchez, P., Segarra, R., … Eguíluz, J. I. (2012). REHACOP: Programa de rehabilitación cognitiva en psicosis. Revista de Neurologia, 54(6), 337–342.
  • Penadés, R., Boget, T., Catalán, R., Bernardo, M., Gastó, C., & Salamero, M. (2003). Cognitive mechanisms, psychosocial functioning, and neurocognitive rehabilitation in schizophrenia. Schizophrenia Research, 63(3), 219–227. https://doi.org/10.1016/S0920-9964(02)00359-6
  • Rado, J., & Hernandez, E. (2014). Schizophrenia. Recent advances in diagnosis and treatment. (M. Janicak, P., Marder, S., Tandon, R., & Goldman, Ed.) (Springer). New York.
  • Robles, Y. (2003). Adaptacion del mini-mental state examination.
  • Rodríguez-Blanco, L., Lubrini, G., Vidal-Mariño, c., Ríos-Lago, M. (2017). Eficacia de la rehabilitación cognitiva de la atención, funciones ejecutivas y memoria operativa en los trastornos psicóticos. Revisión sistemática. Actas Esp Psiquiatr, 45(2), 167–178.
  • Russell, A. J., Munro, J. C., Jones, P. B., Hemsley, D. R., & Murray, R. M. (1997). Schizophrenia and the myth of intellectual decline. American Journal of Psychiatry, 154(5), 635–639. https://doi.org/10.1176/ajp.154.5.635
  • Schmidt, S. J., Mueller, D. R., & Roder, V. (2011). Social cognition as a mediator variable between neurocognition and functional outcome in schizophrenia: Empirical review and new results by structural equation modeling. Schizophrenia Bulletin. https://doi.org/10.1093/schbul/sbr079
  • Snitz, B. E., MacDonald, A. W., & Carter, C. S. (2006). Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: A metaanalytic review of putative endophenotypes. Schizophrenia Bulletin. https://doi.org/10.1093/schbul/sbi048
  • Stuchlik, A., & Sumiyoshi, T. (2014). Cognitive Deficits in Schizophrenia and Other Neuropsychiatric Disorders: Convergence of Preclinical and Clinical Evidence. Frontiers in Behavioral Neuroscience, 8. https://doi.org/10.3389/fnbeh.2014.00444
  • Tarlreja, B. T., Shah, S., & Kataria, L. (2013). Cognitive function in schizophrenia and its association with socio-demographics factors Cognitive function in schizophrenia and its association with sociodemographics factors : Bharti T Talreja , Sandeep Shah , Lakhan Kataria, I …. Industrial Psychiatry Journal, 22(1), 47–53.
  • Teresi, J. A. (2007). Mini-Mental State Examination (MMSE): Scaling the MMSE using item response theory (IRT). Journal of Clinical Epidemiology, 60(3), 256–259. https://doi.org/10.1016/j.jclinepi.2006.06.009
  • Til Wykes, Huddy, V., Cellard, C., McGurk, S., & Czobor, P. (2011). A MetaAnalysis of Cognitive Remediation for Schizophrenia: Methodology and Effect Sizes, (May), 472–485. https://doi.org/10.1176/appi.ajp.2010.10060855
  • Torralva, T., Roca, M., Gleichgerrcht, E., Bonifacio, A., Raimondi, C., & Manes, F. (2011). Validación de la versión en español del Addenbrooke’s Cognitive Examination-Revisado (ACE-R). Neurologia, 26(6), 351–356. https://doi.org/10.1016/j.nrl.2010.10.013
  • Xu, J. Q., Hui, C. L., Longenecker, J., Lee, E. H., Chang, W. C., Chan, S. K., & Chen, E. Y. (2014). Executive function as predictors of persistent thought disorder in first-episode schizophrenia: a one-year follow-up study. Schizophr Res, 159(2–3), 465–470. https://doi.org/10.1016/j.schres.2014.08.022
  • Yun, D. Y., Hwang, S. S. H., Kim, Y., Lee, Y. H., Kim, Y. S., & Jung, H. Y. (2011). Impairments in executive functioning in patients with remitted and non-remitted schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 35(4), 1148–1154. https://doi.org/10.1016/j.pnpbp.2011.03.018
  • Zegarra-Valdivia J, Cazorla E, & Chino-Vilca, B. (2016). Perfil clínico y epidemiológico de pacientes atendidos en el Centro de Salud Mental “ Moisés Heresi ” de Arequipa - Perú , entre los años 2011. Revista de Neuro-Psiquiatria, 79(2), 31–40.
  • Zegarra-Valdivia, J. A. (2015). Funcionamiento ejecutivo, teoría de la mente y toma de decisiones en pacientes estabilizados con esquizofrenia paranoide del sur del Perú. Revista Mexicana de Neurociencia, 16(3), 13–25.
Fuente de los datos: Dialnet