Cambios en la calidad de vida de personas en tratamiento con quimioterapia adyuvante ambulatoria

  1. Ainhoa Ulibarri Ochoa
  2. Iraurgi Castillo, Ioseba
  3. Ruiz de Alegría Fernández de Retana, Begoña
  4. Galego, Vanesa
  5. Sanz Osés, Pilar
  6. Hernández Santos, Mª Esther
  7. Peña Tejera, Carlos
  8. Ugartemendia Ibarbia, Gurutze
Revista:
Metas de enfermería

ISSN: 1138-7262

Año de publicación: 2015

Volumen: 18

Número: 7

Tipo: Artículo

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Otras publicaciones en: Metas de enfermería

Resumen

Objectives: to understand the evolution of quality of life associated with the health of cancer patients during treatment with outpatient adjuvant systemic chemotherapy, and to compare it with the overall population. Method: an observational multicentre longitudinal study applying the SF-12v2 survey on a sample of 247 patients with cancer between 28 and 70-years-of age (initial measurement on their 2nd chemotherapy cycle; second measurement at their last cycle). The Student’s t test for independent data was used for comparison with the overall population, and the Student’s t test for associated data was used for the comparison between both measurements. For all comparisons, the effect size was calculated based on Cohen’s d measurement. Results: 234 persons completed the study. There was a worsening in all SF-12 dimensions. All differences were statistically significant, except for vitality and pain; there was a noticeable worsening in physical function (t= 8.07; p< 0.001; d= 0.55). When compared with the overall population, there were statistically significant differences in all dimensions, except for pain. Worsening was higher when compared with patients at the end of their treatment in the Physical Component Summary (t= 14.4; p< 0.001; d= 0.96) and in the Mental Summary Component (t= 3.2; p< 0.002; d= 0.21). Conclusions: those persons with outpatient chemotherapy will have a worsening in their perception of quality of life at the end of their treatment, and they will perceive a worse quality of life than the overall population in physical dimensions, and to a lower extent in the quality of life of emotional aspects.

Referencias bibliográficas

  • International Agency for Research on Cancer. World Health Organization. Globocan 2012: estimated cancer incidence, mortality and prevalence worldwide in 2012. France: International Agency for Research on Cancer; 2015 [citado 20 jul 2015]. Disponible en: http://globocan.iarc.fr/Pages/fact_sheets_population.aspx
  • Del Barco S, Ciruelos E, Tusquets I., Ruiz M. Barnadas A. SEOM clinical guidelines for the systemic treatment of early breast cancer 2013. Clin Transl Oncol 2013; 15:1011-7.
  • Camps C, Felip E, García-Campelo R, Trigo JM, Garrido P. SEOM clinical guidelines for the treatment of non-small cell lung cancer (NSCLC) 2013. Clin Transl Oncol 2013; 15:977-84.
  • Maurel J, Grávalos C, Rivera F, Vera R, González E. SEOM clinical guidelines for the adjuvant treatment of colorectal cancer 2013. Clin Transl Oncol; 15: 991-5.
  • Broeckel J, Jacobsen PB, Balducci L, Horton J, Lyman GH. Quality of life after adjuvant chemotherapy for breast cancer. Breast Cancer Res Treat 2000; 62(2):141-50.
  • Gil F, Costa G, Hilker I, Benito L. First anxiety, afterwards depression: psychological distress in cancer patients at diagnosis and after medical treatment. Stress and health 2012; 28:362-7.
  • Strauss B, Brix C, Fischer S, Leppert K, Füller J, Roehrig B, et al. The influence of resilience on fatigue in cancer patients undergoing radiation therapy (RT). J Cancer Res Clin Oncol 2007; 133: 511-8.
  • Brix C, Schleussner C, Füller J, Roehrig B, Wendt TG, Strauss B. The need for psychosocial support and its determinants in a sample of patients undergoing radio oncological treatment of cancer. Journal of Psychosomatic Research 2008; 65:541-8.
  • Costa-Requena G, Gil F. Quality of life in the chemotherapy treatment of Spanish cancer patients: a comparison of general population. Psycho-Oncology 2009; 18:1053-9.
  • Etxeberria Y, Pérez-Izquierdo J, Badiola C, Quintana JM, Padierna A, Aróstegui I et al. Evaluación de la calidad de vida en pacientes con cáncer de pulmón. Gac Sanit 2001; 15(1):25-31.
  • Castellano C, Blasco T, Oller A, Pérez-Campdepadrós M, Sánchez De Toledo J, Capdevilla L. Calidad de vida en adolescentes supervivientes de cáncer infantojuvenil. MedClin (Barc) 2009; 133(20):783-6.
  • Kershaw TS, Mood DW, Newth G, Ronis DL, Sanda MG, Vaishampayan U, et al. Longitudinal analysis of a model to predict quality of life in prostate cancer patients and their spouses. Ann Behav Med 2008; 36(2):117-128.
  • Ware JE, Kosinski M, Keller SD. A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care 1996; 34(3):220-33.
  • Vilagut G, Valderas JM, Ferrer M, Garin O, López-García E, Alonso J. Interpretación de los cuestionarios de salud SF-36 y SF-12 en España: componentes físico y mental. MedClin (Barc) 2008; 130 (9):726-35.
  • Gobierno Vasco. Encuesta de salud de la C.A. del País Vasco 2002. Vitoria-Gasteiz: Gobierno Vasco; 2015 [citado 20 jul 2015]. Disponible en: http://www.osakidetza.euskadi.eus/contenidos/informacion/encuesta_salud_historial/es_escav/adjuntos/encuesta2002.pdf
  • Pucheau S, Consoli SM, D´Auzac C, Français P, Issad B. Do health causal attributions and coping strategies act as moderators of quality of life in peritoneal dialysis patients? Journal of Psychosomatic research 2004; 56(3):317-22.
  • Cleary J, Drennan J. Quality of life of patients on haemodialysis for end-stage renal disease. J Adv Nurs 2005; 51(6):577-86.
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