Multigeruza polimerikoakmediku-protesietarako materialen ezaugarriak hobetzeko bidea

Resumen

There is a great demand for new materials in the field of biomedicine to be used as implants, however they cause rejection problems due to their lack of biocom-patibility. In this work two substrates (inorganic and polymeric) will be surface modi-fied using the layer by layer strategy (LbL), in order to construct hyaluronic and chi-tosan multilayers. It has been proven that the layers were successfully built by fluorescent confocal microscopy by means of the increase of fluorescence along layers deposition after fluorescent labelling of chitosan. Thanks to this, it has been possible to increase the hydrophilicity of the surfaces enhancing antibacterial properties and get-ting more biocompatible materials in a simple and inexpensive way.