La biología sintética como desafío para comprender la autonomía de lo vivo

  1. Sara Murillo-Sánchez
  2. Kepa Ruiz-Mirazo
Aldizkaria:
Isegoría: Revista de filosofía moral y política

ISSN: 1130-2097

Argitalpen urtea: 2016

Zenbakia: 55

Orrialdeak: 551-575

Mota: Artikulua

DOI: 10.3989/ISEGORIA.2016.055.08 DIALNET GOOGLE SCHOLAR lock_openSarbide irekia editor

Beste argitalpen batzuk: Isegoría: Revista de filosofía moral y política

Laburpena

En este artículo se ofrece una visión de la biología sintética alternativa a los planteamientos ingenieriles que marcan gran parte de la agenda de investigación del campo. Nuestro análisis se centra en enfoques, teóricos y experimentales, cuyo objetivo fundamental es la comprensión del fenómeno de la vida per se. Una revisión detallada de varios casos de implementación artificial, in vitro, de sistemas químicos ‘auto-productivos’ nos ayudará a reflexionar sobre el enorme reto que supone transformar una disciplina científica eminentemente descriptiva, como la biología, en un proyecto que incluya y potencie líneas de investigación basadas en la idea de síntesis o fabricación. El reto es mayúsculo debido al carácter intrínsecamente metabólico de los sistemas biológicos, lo cual hace que nuestro empeño en controlarlos o en construirlos de novo sea mucho más dificultoso, forzándonos a desarrollar plataformas de intervención/implementación a nivel molecular que no pongan en compromiso esa inherente dimensión autónoma de lo vivo.

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