Benlafaxinaren eragina ezegonkortasun sozial kronikoa jasandako sagu emeen sistema serotoninergiko zentralean eta jokabidean
- Ainitze Labaka
- Eneritz Gómez-Lázaro
- Olatz Goñi-Balentziaga
- Aitor Renteria-Dominguez
- Larraitz Garmendia
ISSN: 2530-9412
Year of publication: 2018
Volume: 2
Issue: 1
Pages: 21-29
Type: Article
More publications in: Osagaiz: osasun-zientzien aldizkaria
Abstract
Women are twice as likely as men to develop depression, and are also more frequently prescribed antidepressant treatments. This sexual disparity is also observable in effectiveness of treatments. Despite this fact, most studies that have used animal models to determine the physiological mechanisms implicated in depression and to develop specific drugs for their treatment have been performed in males. The aim of this study was to analyze the effects of the serotonine and noradrenaline reuptake inhibitor venlafaxine on the behavior and central serotoninergic pathways of female mice subjected to chronic social instability stress.