Alvaro
Villarroel Muñoz
Universidad del País Vasco/Euskal Herriko Unibertsitatea
Lejona, EspañaPublikationen in Zusammenarbeit mit Forschern von Universidad del País Vasco/Euskal Herriko Unibertsitatea (38)
2024
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Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided strategy
Biomedicine and Pharmacotherapy, Vol. 174
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MLe-KCNQ2: An Artificial Intelligence Model for the Prognosis of Missense KCNQ2 Gene Variants
International Journal of Molecular Sciences, Vol. 25, Núm. 5
2023
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Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel
Journal of Biological Chemistry, Vol. 299, Núm. 2
2022
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Gure bihotzeko kalmodulina
Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 42, pp. 173-191
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Microglia-Mediated Inflammation and Neural Stem Cell Differentiation in Alzheimer’s Disease: Possible Therapeutic Role of KV1.3 Channel Blockade
Frontiers in Cellular Neuroscience, Vol. 16
2021
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An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel
BMC Biology, Vol. 19, Núm. 1
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Do calmodulin binding IQ motifs have built-in capping domains?
Protein Science, Vol. 30, Núm. 10, pp. 2029-2041
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KV7.2 kanala: estruktura, erregulazioa eta kitzikagarritasun neuronalean duen ekintza
Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 39, pp. 37-60
2020
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Atomistic insights of calmodulin gating of complete ion channels
International Journal of Molecular Sciences, Vol. 21, Núm. 4
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Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors
Cell Death and Disease, Vol. 11, Núm. 12
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Novel dominant kcnq2 exon 7 partial in-frame duplication in a complex epileptic and neurodevelopmental delay syndrome
International Journal of Molecular Sciences, Vol. 21, Núm. 12, pp. 1-11
2019
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Homomeric Kv7.2 current suppression is a common feature in KCNQ2 epileptic encephalopathy
Epilepsia, Vol. 60, Núm. 1, pp. 139-148
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The crossroad of ion channels and Calmodulin in disease
International Journal of Molecular Sciences, Vol. 20, Núm. 2
2018
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Correction: Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel (Proceedings of the National Academy of Sciences of the United States of America (2018) 115 (2395-2400) DOI: 10.1073/pnas.1800235115)
Proceedings of the National Academy of Sciences of the United States of America
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Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel
Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Núm. 10, pp. 2395-2400
2017
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Differential regulation of pi(4,5)p2 sensitivity of kv7.2 and kv7.3 channels by calmodulin
Frontiers in Molecular Neuroscience, Vol. 10
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Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes
Scientific Reports, Vol. 7
2016
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Ubiquitin-specific protease 36 (USP36) controls neuronal precursor cell-expressed developmentally down-regulated 4-2 (Nedd4-2) actions over the neurotrophin receptor TrkA and potassium voltage-gated channels 7.2/3 (kv7.2/3)
Journal of Biological Chemistry, Vol. 291, Núm. 36, pp. 19132-19145
2015
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An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels
Journal of Cell Science, Vol. 128, Núm. 16, pp. 3155-3163
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Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1852, Núm. 9, pp. 1856-1866