Publicacións (49) Publicacións de Gorka Basañez Asua

2019

  1. BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL

    Cell Death and Differentiation, Vol. 26, Núm. 10, pp. 1880-1894

2018

  1. The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

    Redox Biology, Vol. 14, pp. 164-177

2017

  1. Membrane insertion of the BAX core, but not latch domain, drives apoptotic pore formation

    Scientific Reports, Vol. 7, Núm. 1

2015

  1. Minimalist model systems reveal similarities and differences between membrane interaction modes of MCL1 and BAK

    Journal of Biological Chemistry, Vol. 290, Núm. 27, pp. 17004-17019

2014

  1. Apaf-1 inhibitors protect from unwanted cell death in In vivo models of kidney ischemia and chemotherapy induced ototoxicity

    PLoS ONE, Vol. 9, Núm. 10

  2. Lipid-dependent bimodal mcl1 membrane activity

    ACS Chemical Biology, Vol. 9, Núm. 12, pp. 2852-2863

  3. Specific interaction with cardiolipin triggers functional activation of dynamin-related protein 1

    PLoS ONE, Vol. 9, Núm. 7

2013

  1. Liposomes decorated with Apo2L/TRAIL overcome chemoresistance of human hematologic tumor cells

    Molecular Pharmaceutics, Vol. 10, Núm. 3, pp. 893-904

  2. Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size

    Journal of Biological Chemistry, Vol. 288, Núm. 46, pp. 33241-33252

2012

  1. A New View of the Lethal Apoptotic Pore

    PLoS Biology, Vol. 10, Núm. 9

2011

  1. Reconstitution of proapoptotic BAK function in liposomes reveals a dual role for mitochondrial lipids in the BAK-driven membrane permeabilization process

    Journal of Biological Chemistry, Vol. 286, Núm. 10, pp. 8213-8230

2010

  1. Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

    Biochimica et Biophysica Acta - Bioenergetics, Vol. 1797, Núm. 6-7, pp. 1217-1224

  2. Liposome-bound APO2L/TRAIL is an effective treatment in a rabbit model of rheumatoid arthritis

    Arthritis and Rheumatism, Vol. 62, Núm. 8, pp. 2272-2282

  3. Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

    Cell, Vol. 142, Núm. 6, pp. 889-901

2009

  1. Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangements

    Journal of Biological Chemistry, Vol. 284, Núm. 7, pp. 4200-4212

2008

  1. BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes

    Journal of Biological Chemistry, Vol. 283, Núm. 12, pp. 7790-7803

  2. Mechanism of Mitochondrial Glutathione-Dependent Hepatocellular Susceptibility to TNF Despite NF-κB Activation

    Gastroenterology, Vol. 134, Núm. 5, pp. 1507-1520

  3. Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma

    Cancer Research, Vol. 68, Núm. 13, pp. 5246-5256

  4. Regulation of antiapoptotic MCL-1 function by gossypol: Mechanistic insights from in vitro reconstituted systems

    Biochemical Pharmacology, Vol. 76, Núm. 11, pp. 1563-1576

  5. Unravelling the Bcl-2 apoptosis code with a simple model system

    PLoS Biology, Vol. 6, Núm. 6, pp. 1148-1151