Patricia
Aspichueta Celaá
Centro de Investigación Cooperativa en Biotecnología
Zamudio, EspañaPublications en collaboration avec des chercheurs de Centro de Investigación Cooperativa en Biotecnología (19)
2024
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Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
Cell Reports Medicine, Vol. 5, Núm. 7
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Proceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH)
Gastroenterologia y Hepatologia
2023
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
2022
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Journal of Hepatology, Vol. 76, Núm. 1, pp. 11-24
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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models
Journal of Hepatology, Vol. 77, Núm. 1, pp. 177-190
2021
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease
United European Gastroenterology Journal, Vol. 9, Núm. 7, pp. 848-859
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Journal of Hepatology, Vol. 75, Núm. 1, pp. 34-45
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Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Molecular Metabolism, Vol. 53
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TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Gut, Vol. 70, Núm. 7, pp. 1345-1361
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Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models
Journal of Hepatology, Vol. 74, Núm. 2, pp. 394-406
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The L-α-Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis
Hepatology, Vol. 73, Núm. 2, pp. 606-624
2020
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Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease
Aging Cell, Vol. 19, Núm. 8
2019
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SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
EBioMedicine, Vol. 40, pp. 406-421
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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Molecular Metabolism, Vol. 29, pp. 40-54
2017
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Hepatic p63 regulates steatosis via IKKβ/ER stress
Nature Communications, Vol. 8
2015
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S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease
Journal of Hepatology, Vol. 62, Núm. 3, pp. 673-681
2012
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Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1
Gastroenterology, Vol. 143, Núm. 3