Publicacions (52) Publicacions de Izaskun Buendía Abaitua

2022

  1. Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia

    Autophagy, Vol. 18, Núm. 6, pp. 1297-1317

2021

  1. Factor XII protects neurons from apoptosis by epidermal and hepatocyte growth factor receptor-dependent mechanisms

    Journal of Thrombosis and Haemostasis, Vol. 19, Núm. 9, pp. 2235-2247

  2. Filling the gaps on stroke research: Focus on inflammation and immunity

    Brain, Behavior, and Immunity, Vol. 91, pp. 649-667

2020

  1. Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease

    Antioxidants, Vol. 9, Núm. 8, pp. 1-20

  2. Immune Responses and Anti-inflammatory Strategies in a Clinically Relevant Model of Thromboembolic Ischemic Stroke with Reperfusion

    Translational Stroke Research, Vol. 11, Núm. 3, pp. 481-495

  3. Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization

    Pharmacological Research, Vol. 152

2019

  1. Neuroprotective effects of EpoL against oxidative stress induced by soluble oligomers of Aβ peptide

    Redox Biology, Vol. 24

  2. Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux

    Journal of Pineal Research, Vol. 67, Núm. 1

2018

  1. The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca 2+ dysregulation, and mitochondrial abnormalities

    Journal of Neurochemistry, Vol. 145, Núm. 2, pp. 170-182

  2. Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function

    Nature Communications, Vol. 9, Núm. 1

  3. Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy

    Redox Biology, Vol. 18, pp. 173-180

  4. Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response

    Nature Neuroscience, Vol. 21, Núm. 2, pp. 240-249

2017

  1. Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"

    ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210

  2. ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels

    Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359

  3. Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease

    Scientific Reports, Vol. 7

  4. Heme-Oxygenase i and PCG-1α Regulate Mitochondrial Biogenesis via Microglial Activation of Alpha7 Nicotinic Acetylcholine Receptors Using PNU282987

    Antioxidants and Redox Signaling, Vol. 27, Núm. 2, pp. 93-105

  5. ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

    ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81

  6. Inclusion complex of ITH12674 with 2-hydroxypropyl-β-cyclodextrin: Preparation, physical characterization and pharmacological effect

    Carbohydrate Polymers, Vol. 157, pp. 94-104

  7. Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

    Redox Biology, Vol. 12, pp. 1040-1051

  8. NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 46, pp. 12315-12320