Izaskun
Buendía Abaitua
Postdoctoral researcher
Patrycja
Michalska
Publications dans lesquelles il/elle collabore avec Patrycja Michalska (13)
2020
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Antioxidant, anti-inflammatory and neuroprotective profiles of novel 1,4-dihydropyridine derivatives for the treatment of alzheimer’s disease
Antioxidants, Vol. 9, Núm. 8, pp. 1-20
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Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization
Pharmacological Research, Vol. 152
2019
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Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux
Journal of Pineal Research, Vol. 67, Núm. 1
2017
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Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia"
ACS chemical neuroscience, Vol. 8, Núm. 1, pp. 210
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Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease
Scientific Reports, Vol. 7
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ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia
ACS Chemical Neuroscience, Vol. 8, Núm. 1, pp. 67-81
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Inclusion complex of ITH12674 with 2-hydroxypropyl-β-cyclodextrin: Preparation, physical characterization and pharmacological effect
Carbohydrate Polymers, Vol. 157, pp. 94-104
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Novel multitarget hybrid compounds for the treatment of alzheimer’s disease
Current Topics in Medicinal Chemistry, Vol. 17, Núm. 9, pp. 1027-1043
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Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices
Neuropharmacology, Vol. 116, pp. 110-121
2016
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Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
Pharmacology and Therapeutics, Vol. 157, pp. 84-104
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The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators
Journal of Medicinal Chemistry, Vol. 59, Núm. 21, pp. 9967-9973
2015
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Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models
Neuropharmacology, Vol. 99, pp. 187-195
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New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection
Future Medicinal Chemistry, Vol. 7, Núm. 15, pp. 1961-1969