Hector
Flores Romero
Principal Investigator
Publicacións (20) Publicacións de Hector Flores Romero
2024
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Crosstalk between mitochondria–ER contact sites and the apoptotic machinery as a novel health meter
Trends in Cell Biology
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Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
Cell Death Discovery, Vol. 10, Núm. 1
2023
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Exploring the Binding Affinity of the ARR2 GARP DNA Binding Domain via Comparative Methods
Genes, Vol. 14, Núm. 8
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Mitochondrial pores at the crossroad between cell death and inflammatory signaling
Molecular Cell, Vol. 83, Núm. 6, pp. 843-856
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Visualization of BOK pores independent of BAX and BAK reveals a similar mechanism with differing regulation
Cell Death and Differentiation, Vol. 30, Núm. 3, pp. 731-741
2022
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BCL-2-family protein tBID can act as a BAX-like effector of apoptosis
EMBO Journal, Vol. 41, Núm. 2
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Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer
Cellular and Molecular Life Sciences, Vol. 79, Núm. 6
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MERLIN: A BRET-Based Proximity Biosensor for Studying Mitochondria–ER Contact Sites
Methods in Molecular Biology (Humana Press Inc.), pp. 197-205
2020
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A lipid perspective on regulated cell death
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 197-236
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Lipids glue BAK dimers together
Nature Structural and Molecular Biology
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Merlin: A novel BRET-based proximity biosensor for studying mitochondria–ER contact sites
Life Science Alliance, Vol. 3, Núm. 1
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Pore formation in regulated cell death
EMBO Journal, Vol. 39, Núm. 23
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The mysteries around the BCL‐2 family member BOK
Biomolecules, Vol. 10, Núm. 12, pp. 1-14
2019
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BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL
Cell Death and Differentiation, Vol. 26, Núm. 10, pp. 1880-1894
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MAVS-induced mitochondrial membrane remodeling
FEBS Journal
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The Incomplete Puzzle of the BCL2 Proteins
Cells, Vol. 8, Núm. 10
2017
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Membrane insertion of the BAX core, but not latch domain, drives apoptotic pore formation
Scientific Reports, Vol. 7, Núm. 1
2015
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BAK proteinaren mekanismo proapoptotikoa aztertzen
I. IkergazteNazioarteko ikerketa euskaraz. Kongresuko artikulu-bilduma: 2015eko maiatzaren 13, 14 eta 15a. Durango, Euskal Herria
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BCL2-related ovarian killer (BOK) proteinak heriotza zelularprogramatuan eta mitokondrioen morfologiaren eraldaketan parte hartzen du
I. IkergazteNazioarteko ikerketa euskaraz. Kongresuko artikulu-bilduma: 2015eko maiatzaren 13, 14 eta 15a. Durango, Euskal Herria
2014
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Lipid-dependent bimodal mcl1 membrane activity
ACS Chemical Biology, Vol. 9, Núm. 12, pp. 2852-2863