Structural Biology of Disease Mechanisms Laboratory
Memorial Sloan Kettering Cancer Center
Nueva York, Estados UnidosPublications en collaboration avec des chercheurs de Memorial Sloan Kettering Cancer Center (3)
2020
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Substrate interaction inhibits γ-secretase production of amyloid-β peptides
Chemical Communications, Vol. 56, Núm. 17, pp. 2578-2581
2011
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Structure of γ-secretase and its trimeric pre-activation intermediate by single-particle electron microscopy
Journal of Biological Chemistry, Vol. 286, Núm. 24, pp. 21440-21449
2008
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Soluble oligomers of the intramembrane serine protease YqgP are catalytically active in the absence of detergents
Biochemistry, Vol. 47, Núm. 46, pp. 11920-11929