Amanda
Sierra Saavedra
Principal Investigator
Publicacions en què col·labora amb Amanda Sierra Saavedra (16)
2020
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Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome
The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 40, Núm. 7, pp. 1453-1482
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Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy
Epilepsia, Vol. 61, Núm. 11, pp. 2593-2608
2019
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Reactive Disruption of the Hippocampal Neurogenic Niche After Induction of Seizures by Injection of Kainic Acid in the Amygdala
Frontiers in Cell and Developmental Biology, Vol. 7
2018
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ProMoIJ: A new tool for automatic three-dimensional analysis of microglial process motility
GLIA, Vol. 66, Núm. 4, pp. 828-845
2017
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A standardized protocol for stereotaxic intrahippocampal administration of kainic acid combined with electroencephalographic seizure monitoring in mice
Frontiers in Neuroscience, Vol. 11, Núm. MAR
2016
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Clearing the corpses: Regulatory mechanisms, novel tools, and therapeutic potential of harnessing microglial phagocytosis in the diseased brain
Neural Regeneration Research, Vol. 11, Núm. 10, pp. 1533-1539
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Erratum: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling (PLoS Biology (2016) 14:5 (e1002466) DOI: 10.1371/journal.pbio.1002466)
PLoS Biology
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Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
PLoS Biology, Vol. 14, Núm. 5
2015
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Longitudinal variations of brain functional connectivity: A case report study based on a mouse model of epilepsy
F1000Research, Vol. 4
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Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis
Cell Stem Cell, Vol. 16, Núm. 5, pp. 488-503
2014
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Surveillance, phagocytosis, and inflammation: How never-resting microglia influence adult hippocampal neurogenesis
Neural Plasticity, Vol. 2014
2013
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A developmental perspective on adult hippocampal neurogenesis
International Journal of Developmental Neuroscience, Vol. 31, Núm. 7, pp. 640-645
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Janus-faced microglia: Beneficial and detrimental consequences of microglial phagocytosis
Frontiers in Cellular Neuroscience
2012
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Neural stem cell deforestation as the main force driving the age-related decline in adult hippocampal neurogenesis
Behavioural Brain Research, Vol. 227, Núm. 2, pp. 433-439
2011
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Adult human neurogenesis: From microscopy to magnetic resonance imaging
Frontiers in Neuroscience
2010
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Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis
Cell Stem Cell, Vol. 7, Núm. 4, pp. 483-495