Laboratory of Humanized Models of Disease
University College London
Londres, Reino UnidoPublikationen in Zusammenarbeit mit Forschern von University College London (6)
2023
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MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease
Science (New York, N.Y.), Vol. 381, Núm. 6663, pp. 1176-1182
2021
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Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques
Molecular Neurodegeneration, Vol. 16, Núm. 1
2019
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PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome
Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Núm. 1, pp. 277-286
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Stem-cell-derived human microglia transplanted in mouse brain to study human disease
Nature Neuroscience, Vol. 22, Núm. 12, pp. 2111-2116
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The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications
The Lancet Neurology, Vol. 18, Núm. 4, pp. 406-414
2017
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Tetraspanin 6: A pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments
Molecular Neurodegeneration, Vol. 12, Núm. 1