Hydroxyapatite and graphene oxide on nanocellulose-alginate ink for 3D bioprinting and bone regeneration
- Markel Lafuente Merchan 123
- Sandra Ruiz Alonso 123
- Laura Saenz del Burgo Martínez 123
- José Luis Pedraz Muñoz 123
- 1 NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain
- 2 Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN),Vitoria-Gasteiz, Spain.
- 3 Bioaraba, NanoBioCel Reseach Group, E-01009 Vitoria-Gasteiz, Spain
ISSN: 2660-6356
Ano de publicación: 2021
Título do exemplar: XV CONGRESO DE LA SOCIEDAD ESPAÑOLA DE FARMACIA INDUSTRIA Y GALÉNICA
Volume: 2
Número: 2
Páxinas: 187-188
Tipo: Artigo
Outras publicacións en: RESCIFAR Revista Española de Ciencias Farmacéuticas
Resumo
The incidence of bone-related diseases has been increasing due to aging of the population. Up to now, therapeutic approaches have been focused on graft and titanium implants, which have been associated with infection, pain and implant rejection. Tissue engineering has become a promising treatment due to the use of scaffolds, which are designed to imitate as closely as possible the native tissue. In addition, three-dimensional (3D) bioprinting has become an emerging additive manufacturing technology in tissue engineering because of its rapid prototyping capacity and the possibility of creating complex structures. This study is focused on the development of nanocellulose-alginate (NC-Alg) based bioinks for 3D bioprinting for bone regeneration. Furthermore, hydroxyapatite (HAP) and graphene oxide (GO) were incorporate as they are biocompatible, bioactive and osteoconductive materials